PSORIASIS

PSORIASIS

A common condition that changes the life cycle of skin cells

In detail, what is Psoriasis?

Psoriasis occurs when skin cells multiply too fast. Normally the skin renews itself every 3 or 4 weeks. In psoriasis sufferers it happens every 3 to 7 days. This overproduction breaks down the protective skin barrier, allowing the escape of moisture and the build-up of plaques of thick, scaling skin.

Symptoms include red and inflamed skin, often covered with loose, silver-coloured scales. The affected skin can be itchy and painful; sometimes it cracks and bleeds.

Psoriasis can really affect your quality of life. The visible symptoms can often make you self-conscious, and the constant itching can be annoying and exhausting. Many psoriasis sufferers try different solutions, always looking for a more effective product to treat their symptoms. To make matters worse, some treatments lose their efficacy over time, forcing sufferers to constantly switch between treatments.

Healthy skin

Healthy skin

Psoriasis skin

Psoriasis skin

Symptoms

There are different types of psoriasis and the condition affects sufferers in various ways and grades of severity. Symptoms may range from barely noticeable to outbreaks that cover most of the body.

(infographic)

QUESTIONS WE OFTEN GET
What are the types of psoriasis?

Psoriasis appears in a variety of types with distinct characteristics. There seven types: psoriasis vulgaris (plaque), guttate, inverse, pustular, erythrodermic, nail psoriasis and psoriatic arthritis. The most common is psoriasis vulgaris (80% of all sufferers).

What are the types of psoriasis severity?

Mild psoriasis: symptoms cover 3% of your body.

Moderate psoriasis: symptoms cover up to 10% of your body.

Severe psoriasis: symptoms cover more than 10% of your body.

Can psoriasis affect nails?

Yes, psoriasis can also affect the fingernails and toenails, causing pitting, thickening and irregular contour of the nail.

Can psoriasis affect the ears or face?

Psoriasis can occur in the external ear canal and behind the eardrum in the inner ear. If you develop psoriasis in the ear It is not uncommon to also see it on your face: around the eyes, nose and mouth.

What causes psoriasis?

The exact cause is unknown. But scientists believe that it is a multifactorial disorder: caused by a combination of several genetic mutations, stress and environmental triggers.

Is psoriasis contagious?

Psoriasis is not contagious.

Is psoriasis hereditary (genetic) ?

Yes, about 1/3 of patients with psoriasis have a parent or siblings with psoriasis. However, the development of the disease is quite complex. It results from a combination of genetic (inherited), immunologic and environmental factors.

What triggers Psoriasis?

What causes psoriasis?

The predisposition for psoriasis is believed to be genetic, and there is no definitive cure. It can develop at any age.

While the exact causes remain unknown, there are indications that an auto-immune disorder is responsible, causing immune system T cells that usually attack bacteria or viruses, to mistakenly attack healthy skin cells. T cell activity also stimulates the overproduction of skin cells.

A vicious cycle results, where the blood vessels are dilated, allowing more white blood cells than usual to enter the skin’s outer layer. This creates increased production of healthy cells, T cells and other white blood cells. In turn yet more white blood cells move to the outer layer, and so the cycle continues.

This underlying genetic condition combines with physical and environmental triggers to cause psoriasis.

psoriasis-trigger

What triggers psoriasis?

It is the result of flare-ups that can be triggered by different substances and physical conditions, such as:

Injury to the skin

Any type of cut, graze, insect bite, infection or severe sunburn can trigger the condition. The so-called Koebner phenomenon also plays a role here, which is when new psoriasis outbreaks occur on what is referred to as “lines of trauma”. In other words, the condition can flare up at the site of any skin injury.

Excessive alcohol consumption

Alcohol plays a dual negative role, by increasing the risk of developing psoriasis and hampering the effectiveness of treatments.

Smoking

Smoking has been shown to double the chances of developing psoriasis. It is particularly linked to a form of pustular psoriasis on the soles of the feet and palms of the hands. It also makes it more difficult to successfully treat the symptoms

Throat and respiratory infections

These infections coincide with psoriasis outbreaks of a particular type, known as guttate psoriasis. Psoriasis can be therefore be triggered by strep throat, colds and flu, bronchitis and so on.

Stress

It has been established that stress affects the immune system, causing it to react in the same way as to physical injury or infection. This contributes to the cycle of overproduction of skin cells.

Certain medicines

These include lithium, some high blood pressure and heart medications (like beta blockers), and anti-malarial drugs.

Hormonal changes

These are often the triggers for the first outbreak of psoriasis, particularly during puberty or menopause. It can have a somewhat unpredictable effect during pregnancy: symptoms can improve or disappear while a woman is pregnant, only to flare up after she has given birth.

QUESTIONS WE OFTEN GET
Is psoriasis caused by stress?

The development or severity of psoriatic lesions is often associated with stress that influences the immune system.

Does alcohol trigger psoriasis?

Heavy drinkers with a family history of psoriasis have a higher risk of incidence of the condition, especially younger men. Alcohol can make treatment less effective and impact immunity too.

What foods should I avoid?

There's no strong scientific evidence that a specific diet can cause or impact psoriasis, but there is evidence that losing extra weight can ease symptoms. A good, balanced diet improves also the beneficial microflora in the guts that supports the functioning of your immune system.

What cures exist?

Psoriasis cannot be cured. It is an auto-immune disorder which causes your immune system to send out faulty signals that speed up the growth cycle of skin cells. Although there’s no cure, you can try to manage the condition and prevent flare-ups.

Who has Psoriasis

Who has psoriasis?

psoriasis-trigger

Psoriasis affects 2 to 3 % of the total population1. Worldwide more than 120-million people suffer from this serious skin condition2. Men and women are equally affected. It can occur at any age, but is especially prevalent between the late teens and the 30s, and between the ages of 50 and 60

Perhaps the most significant risk factor is having a family history of psoriasis. If you have one parent with psoriasis it increases your risk of developing it yourself by around 30%. If both your parents have the condition, the risk rises to around 75%.

1. https://www.psoriasis.org/about-psoriasis

2. https://www.psoriasis.org/cure_known_statistics

QUESTIONS WE OFTEN GET
How do I treat scalp psoriasis?

Scalp psoriasis is characterized by raised, reddish, often scaly patches and can even affect your entire scalp. It can also spread to your forehead, the back of your neck, or behind your ears. On the scalp, psoriasis may need different treatment. The skin on the scalp is thicker and hair can get in the way. So it is more convenient to use specific products for scalp psoriasis.

Is there a shampoo to prevent scalp psoriasis?

There are medicated shampoos on the market to help you manage your scalp psoriasis.

How do I prevent psoriasis flare-ups?

These are just some lifestyle adjustments that you can follow but should not be seen as substitutes for medical treatment and therapy. These include but are not limited to: shower routine (limit to 10mins with lukewarm water, non-irritating soap and moisturising afterwards), wear looser-fitting soft clothing, eat nutritiously and avoid smoking.

How do I apply Dermalex Psoriasis cream?

Apply the cream 2 to 3 times a day to suitably cleansed skin and massage gently into the affected areas. The cream can be used on daily basis as long as the symptoms persist [17].

Please read the full instruction for use before using the product.

Should I apply Dermalex

Apply the cream after washing.

Is Dermalex Psoriasis cream safe to use around the eyes?

Based on the ingredients in the formulation and its physical mode of action, we believe Dermalex Psoriasis cream is safe to use around the eyes, as it does not contain steroids or keratolytic substances. However, as skin around the eyes is thin and sensitive, always use the treatment with caution. Avoid contact with the eyes. In case of contact, rinse thoroughly with water [17]

How to treat Psoriasis

How to treat psoriasis?

There is still no cure for psoriasis, but by avoiding triggers and using an adequate treatment flare-ups can be managed. Depending on the severity of the affliction, different treatments and products are used to relieve the symptoms and help prevent future outbreaks.

First line treatment

Effective treatment of the symptoms begins with moisturizing the skin. As psoriasis is a dry skin condition, it’s important to keep the skin well moisturised with a special moisturizing cream or lotion.

Creams containing coal tar, a substance that helps to slow down the growth of skin cells, can also be used, but these are not popular because of their strong, unpleasant smell.

More advanced treatment

If these don’t treat the symptoms successfully, treatment can be stepped up to include prescription topical treatments, such as vitamin D creams, lotions, and ointments to slow down the skin growth. Topical steroids can also be used to fight the inflammation.

For severe cases

  • UV light therapy (phototherapy)
  • Oral or injected prescription medicines.

Dermalex Psoriasis Cream

This cream is formulated to relieve the symptoms of psoriasis by helping to repair the protective skin barrier. The product is suitable for long-term use.[15].

In all cases, no matter what treatments are used, a healthy diet and good personal hygiene are also strongly advised.

Prevention

Dermalex Psoriasis Creams

Dermalex offers a cream and a gel to aid in the relief of mild to moderate psoriasis:

  • Dermalex Psoriasis Cream to help relieve body psoriasis
  • Dermalex Scalp Psoriasis Gel to help relieve scalp psoriasis symptoms (common in 50% off all psoriasis sufferers)

Dermalex helps to prevent future outbreaks of psoriasis with a unique triple action:

  • The unique MagneoliteTM complex [16] in Dermalex helps repair the skin barrier and creates a protective layer on top of the skin to prevent moisture from escaping.
  • The protective layer also prevents allergens and foreign particles from entering the skin.

The cream aids in maintaing the integrity of the barrier of the skin, and therefore it:

  • Helps regulate the growth of skin cells and helps reduce the scaling.
  • Helps reduce irritation, itching and redness.

Dermalex Psoriasis and Dermalex Scalp Psoriasis contain no steroids, are suitable for long-term use [15, 17].

This product is a medical device.

15. K, N., PASI-based clinical efficacy of Dermalex Psoriasis. 2006.

16. International, O.P., A unique trademarked complex, MagneoLite as the key ingredient of the product. 2015.

17. Fritz K, B.B., Scherer J, Open Label Clinical Study with Dermalex Psoriasis. 2008.

18. Levi-Schaffer, F., et al., Inhibition of proliferation of psoriatic and healthy fibroblasts in cell culture by selected Dead-sea salts. Pharmacology, 1996. 52(5): p. 321-8.

19. K, F., Open Label Study on Efficacy and Acceptance of Dermalex Scalp Psoriasis. 2011-2012.

 

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Solutions by Dermalex

Dermalex Psoriasis Scalp Gel

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Dermalex Psoriasis Cream

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